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Study Suggests Second-generation Antipsychotics are Not Much Better than Haldol in Treating Schizophrenia

Second generation "Atypical" antipsychotic drugs are not much better than the older, less expensive Haldol treating a first episode of schizophrenia, according to a study done by Dutch researchers that was published in the British Medical journal "The Lancet". However,...

Posted by szadmin on March 31, 2008 11:50 AM

Clinical Research Studies on Schizophrenia Recruiting Participants

There are two new research studies recruiting participants at the Clinical Research Unit at the University of North Carolina at Chapel Hill: Following is a description of each of the studies: GLAD - Prevention of Postpsychotic Depression with Lamotrigine Who...

Posted on July 13, 2007 11:06 AM

"Old" Versus "New" Medications for Schizophrenia

Dr. Henry A. Nasrallah, an expert in the field of schizophrenia treatment, was inteviewed by Medscape to discuss results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) as well as Britain's Cost Utility of the Latest Antipsychotic Drugs in...

Posted by Naomi_NJW on June 1, 2007 7:20 AM

Seroquel XR (Extended-Release) Approved for Schizophrenia

The U.S. Food and Drug Administration (FDA) has approved Seroquel (quetiapine fumarate) XR extended-release tablets for the treatment of schizophrenia. Seroquel XR is a product of AstraZeneca. The new extended-release formulation of Seroquel is intended as a once-daily medicine for...

Posted by Naomi_NJW on May 18, 2007 10:15 AM

FDA orders AstraZeneca to Modify Promotions on Seroquel

The FDA's Division of Drug Marketing, Advertising and Communications, in a Nov. 16 letter (see below) to AstraZeneca, said the material is "false and misleading" because it minimized the risk of diabetes and did not adequately communicate the risk of...

Posted by szadmin on November 30, 2006 8:18 AM

Astra Zeneca submits New Drug Application for Sustained Release Seroquel

Schizophrenia.com member Rcourtade noted that on July 18th it was announced that AstraZeneca had submitted a New Drug Application (NDA) to the US Food and Drug Administration for a sustained release (SR) once-daily formulation of Seroquel for the treatment of...

Posted by szadmin on July 24, 2006 11:47 PM

Best Schizophrenia Drug? more CATIE 2 Study Results

Earlier this week we covered the release of the results from the CATIE 2 drug comparison study funded by the National Institute of Mental Health. Instead of focusing on how some symptom or side effect waxes and wanes, the government...

Posted by szadmin on April 12, 2006 1:34 PM

CATIE News & Commentary

The results from the CATIE study that were made public the other day (see CATIE STUDY RESULTS) are provoking a great deal of discussion and analysis in the world of people impacted by schizophrenia - as it well should. The...

Posted by szadmin on September 21, 2005 6:43 PM

CATIE Results - Perphenazine almost as good as newer drugs

The Wall Street Journal reported this morning that "Old Schizophrenia Drug Works As Well as Newer Treatments" In the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) results an older, less expensive antipsychotic drug known as Perphenazine (Trilafon) worked almost as...

Posted by szadmin on September 20, 2005 12:42 PM

CATIE study results this Thursday

Its been reported that this coming Thursday (September 22nd) will see the publishing of the CATIE trial results - the biggest ever government study comparing the safety and efficacy of four big-selling schizophrenia treatments. It is expected to be published...

Posted by szadmin on September 17, 2005 9:52 AM

Adjunctive Topiramate for Treatment Resistant Schizophrenia

A new study suggests that using the drug topiramate in addition to antipsychotic medication may be helpful for 10%-20% of those with treatment-resistant schizophrenia. According to the researchers in the study less than 50% of those suffering from schizophrenia get...

Posted on August 23, 2005 6:08 PM

CATIE Study - New Schizophrenia Treatment Standards Coming

In the coming months the results of a recently-completed study funded by the National Institutes of Mental Health (NIMH) will be published. The study is called CATIE, "The Clinical Antipsychotic Trials of Intervention Effectiveness project" and is comprised of four...

Posted on July 27, 2005 2:41 PM

Seroquel Effective Against Aggression?

Seroquel is effective against aggression in patients with schizophrenia The majority of people suffering from schizophrenia are not violent. However, there seems to be a misconception about the disorder, in that many people perceive those suffering from schizophrenia as being...

Posted on July 8, 2005 9:13 PM

Meds Improve Cognitive Functioning?

SCHIZOPHRENIA; Seroquel and risperidone improve cognitive function Recently, results from a new study conducted by AstraZeneca, show that Seroquel and risperidone are effective "in improving cognitive function, such as memory and attention, in patients with schizophrenia." Though, this is good...

Posted on June 26, 2005 4:07 PM

Risperdal Increases Tumor Risk?

J&J's Risperdal Linked to Increased Tumour Risk Though we've already covered Johnson & Johnson's development of new antipsychotics to some extent, recently some new studies concerning the effects of their antipsychotic Risperdal have been made public. These "preliminary studies," conducted...

Posted on June 23, 2005 3:45 AM

Schizophrenia, Meds & Side Effects

Schizophrenia And Medication Side Effects Recently there has been a lot of news about the medications used for treating schizophrenia. From Florida's possible drug restrictions for Medicaid patients to Eli Lilly's recent "announcement to spend $690 million to end lawsuits...

Posted on June 15, 2005 11:50 PM

FDA Warning - Alzheimers /Antipsychotics

FDA Warning on Antipsychotic Drugs for Elderly suffering from Dementia The U.S. Food and Drug Administration warned Monday that "off-label" -- unapproved -- use of certain drugs used to treat behavioral disorders such as schizophrenia can be potentially fatal to...

Posted by szadmin on April 12, 2005 5:18 AM

New Schizophrenia Meds

Early reports are good on Akzo Nobel's new schizophrenia and bipolar disorder drug called Asenapine, currently in Phase-III trials, (Phase III trials are the final stage of the FDA drug approval process, but there are no guarantees that the drug...

Posted by szadmin on March 24, 2005 6:26 PM

New Drug to Reduce Side Effects

The following is a press release from Acadia Pharmaceuticals, detailing the clinical testing of a new drug that allegedly reduces some side effects associated with haloperidol, Zyprexa, Risperdal and Seroquel. As with all cases where you're getting information directly from...

Posted on September 17, 2004 1:13 AM

Safety and Effectiveness of Long-acting Risperdal

Safety and Efficacy of Long-Acting Risperidone in Schizophrenia: A 12-Week, Multicenter, Open-Label Study in Stable Patients Switched From Typical and Atypical Oral Antipsychotics. Lindenmayer JP, Eerdekens E, Berry SA, Eerdekens M. J Clin Psychiatry. 2004 Aug;65(8):1084-1089. Pharmaceutical companies have recently...

Posted on August 31, 2004 6:57 PM