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Study Suggests Second-generation Antipsychotics are Not Much Better than Haldol in Treating Schizophrenia
Second generation "Atypical" antipsychotic drugs are not much better than the older, less expensive Haldol treating a first episode of schizophrenia, according to a study done by Dutch researchers that was published in the British Medical journal "The Lancet". However,...
Another Study Shows Metformin Effective in Helping Minimize Weight Gain when Using Antipsychotic Medications
There is good news for people fighting weight gain due to antipsychotic medications. In the past year studies have come out that indicate that the common medication side effects of increased weight gain can be minimized or eliminated by good...
FDA Declines to Approve Long-Acting Form of Zyprexa
Eli Lilly has announced this week that the FDA has declined to approve a long-acting, injectable form of their top-selling drug Zyprexa. We covered this new medication that was being developed by Eli Lilly a few weeks ago - you...
Long-Acting Zyprexa Works, But Has Sedation Risks
The Food and Drug Administration (FDA) announced today that a long-acting, injectable form of Eli Lilly & Co.'s medication called Zyprexa was effective at treating schizophrenia but caused "profound sedation" in about 1% of patients. This new version of Zyprexa...
Hearing "Messages" An Early Sign of Schizophrenia?
Hallucinations are one of the positive symptoms people with schizophrenia may experience. A new study conducted by Yale School of Medicine researchers followed 43 participants showing early signs of schizophrenia over a two-year period and discovered that "a tendency to...
Eli Lilly Updates Label Warning for Zyprexa to Better Inform on Side-Effects
Eli Lilly, the maker of Zyprexa, said that new label changes were made as part of ongoing talks with the Food and Drug Administration (FDA). The company said that the new labels include warnings on weight gain and higher levels...
Generic Zyprexa (Olanzapine) Moving Towards Approval in Europe
The European Medicines Agency (EMEA) has recently recommended approval of a generic version of Eli Lilly's schizophrenia treatment Zyprexa (olanzapine). Zyprexa is currently the worlds top selling schizophrenia medication, with global sales in excess of over $4.7 billion in 2006....
Clinical Research Studies on Schizophrenia Recruiting Participants
There are two new research studies recruiting participants at the Clinical Research Unit at the University of North Carolina at Chapel Hill: Following is a description of each of the studies: GLAD - Prevention of Postpsychotic Depression with Lamotrigine Who...
Canada and Germany Attempt To Offer Generic Zyprexa
Canadian Federal Court and the German Patent Court, have applied to gain generic rights to the drug Zyprexa. but drug company Eli Lilly, which owns the rights to Zeprexa, have appealed this. Lilly claims that creating a generic substitution will...
UK Issues Warning About Fake Zyprexa 10mg Tablets
The United Kingdom (UK) Medicines and Healthcare products Regulatory Agency (MHRA), an executive agency of the Department of Health in the UK, has issued a press release warning its citizens using Zyprexa (olanzapine) of the existence of three counterfeit batches...
New Weight Gain Prevention Study for Patients Taking Zyprexa
Obecure, Inc. -- an Isreal-based pharmaceutical company -- has conducted the first initiation visit for its Phase II clinical trial to evaluate the efficacy of the company's OBE101 drug candidate for prevention of weight gain in patients treated with Zyprexa,...
States Turn to Pharma to Help Lower Drug Costs
Today's New York Times has an interesting article on the struggle that the states are having to lower their drug costs for medicaid programs. It notes that "Many states, looking to rein in the cost of expensive antipsychotic drugs like...
How Antipsychotic Drugs Cause Weight Gain
John Hopkins University Researchers Uncover Cause of Antipsychotic-related Drug Weight Gain Johns Hopkins University brain scientists have announced that they understand how and why some of the antipsychotic drugs used for treating schizophrenia cause patients to frequently gain significant weight...
Lilly to Pay Up to $500 Million to Settle Zyprexa Lawsuits
The New York Times reported today that Eli Lilly will pay up to $500 million to settle approximately 18,000 lawsuits from people who claimed they developed diabetes or other diseases after taking Zyprexa, Lilly's antipsychotic medication used for treatment of...
Eli Lilly Said to Have Down-played Zyprexa Diabetes Risks
The New York Times reported this past weekend that "Indianapolis-based drug maker Eli Lilly and Co. has engaged in a decadelong effort to downplay the health risks of Zyprexa, its best-selling medication for schizophrenia, according to hundreds of internal Lilly...
Pfizer Working on New Schizophrenia Drugs
Bloomberg.com is reporting today that Pfizer is busy working on some improved schizophrenia drugs. Given the increasing number of studies that are suggesting that the current schizophrenia medications are no better than the drugs that were available 25 years ago...
Hyperthermia Can Be a Serious Risk for Those with Schizophrenia
A 41 year old woman diagnosed with schizophrenia died of hyperthermia (over-heating) in her home last week. Her daughter believes her schizophrenia prevented her from realizing she was too hot, and taking "normal" steps to cool down; like use the...
Best Schizophrenia Drug? more CATIE 2 Study Results
Earlier this week we covered the release of the results from the CATIE 2 drug comparison study funded by the National Institute of Mental Health. Instead of focusing on how some symptom or side effect waxes and wanes, the government...
Schizophrenia Drug Research Bias
The Washington Post reported this week on a new academic study covered in the American Journal of Psychiatry that suggests there is a significant bias in research studies done by some pharmaceuticals companies. Specifically the newspaper reported: Pharmaceutical giant Eli...
Zyprexa Patent Battle Continues
The Indianapolis Star reports that the makers of generic drugs to appeal; 3 companies will continue efforts to get share of the billions spent on the antipsychotic drug. Generic Drug Companies Challenge Lilly's Patent on Zyprexa The Indianapolis Star stated...
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