Schizophrenia Research Study with Need for Participants:
Jewish and Non-Jewish Families Needed
- I encourage everyone to participate in these if appropriate. Obviously
the better the research these organizations can do, the faster they can
find solutions to the problems of Schizophrenia and the faster people can
get improved treatment. - Brian.
- From Lucus Kempf, at John Hopkins University:
- I was wondering if you could post our request for families to participate
in a genetic study? Here is a sample of our flyer for the Jewish community
but we are also interested in finding families who are not Jewish.
- Family Studies in Schizophrenia and Bipolar Disorder in The Jewish
- The Johns Hopkins School of Medicine has been a leader in the fields
of genetics and psychiatry for many years. A team of investigators headed
by Dr. Ann Pulver is investigating the genetic basis for schizophrenia
and bipolar disorder in the Ashkenazi Jewish Community. Prior research
has indicated that the susceptibility to both these disorders is associated
with genetic factors. Recent advances in molecular biology and statistical
genetics now make it possible to identify and describe the specific genes
that cause such complex diseases as schizophrenia and bipolar disorder.
This knowledge will be used by researchers to help develop new treatments
for these diseases.
- LINKAGE STUDIES
- Using genetic analysis, scientists can track small parts of each chromosome
through a family and determine whether the occurrence of a specific disease
or trait is associated with the presence or absence of ome chromosome marker.
Using the results obtained from many families, scientists get clues as
to which segment of a chromosome is most likely to contain a gene involved
in schizophrenia or bipolar disorder. Thus, a particular area of a chromosome
is "linked" to schizophrenia or bipolar disorder.
- PROGRESS IN THE SEARCH FOR A GENETIC BASIS FOR SCHIZOPHRENIA AND
- For both disorders, linkages on several chromosomes have been reported.
Specific genes have not been identified. One of the limiting factors in
this work is the availability of appropriate families for the participation
in this research.
- WHY STUDY THE ASHKENAZI
- JEWISH COMMUNITY?
- The Ashkenazi Jewish Community is a relatively genetically homogenous
ethnic group and provides a unique opportunity to contribute to our understanding
of the genes involved in schizophrenia and bipolar disorder. The identification
of susceptibility genes in the Jewish Community will hopefully lead to
the development of new medications for these diseases.
- WHICH FAMILIES ARE ELIGIBLE
- FOR THE STUDY?
- Ashkenazi Jewish Families with TWO OR MORE SIBLINGS diagnosed with
schizophrenia or bipolar disorder, and who have AT LEAST ONE LIVING PARENT.
- Or Ashkenazi Jewish Families with BOTH PARENTS LIVING and AN OFFSPRING
diagnosed with schizophrenia or bipolar disorder.
- WHAT WILL BE REQUIRED OF PARTICIPANTS?
- Participants will participate in a confidential interview which includes
family history and diagnostic clinical assessment questions. They will
be asked to sign consents for relevant medical records, and to donate a
small blood sample. Participants do not have to travel.
- REFERRAL PROCEDURES
- Families may be referred by a clinician or may contact us
- directly. Clinicians who know of families that may be eligible can
contribute to this research by talking to patients and/or their relatives.
If you would like to help or know more visist our website at http://www.med.jhu.edu/gene_epi/flyer.html
or contact us toll free at 1-888-289-4095.
You can also send email to: email@example.com
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