March 24, 2005

New Schizophrenia Meds

Early reports are good on Akzo Nobel's new schizophrenia and bipolar disorder drug called Asenapine, currently in Phase-III trials, (Phase III trials are the final stage of the FDA drug approval process, but there are no guarantees that the drug will pass this phase of trials, or that it will ultimately be sold to the public). Pharmacuetical company Solvay is also in final testing with its new drug -- Bifeprunox -- which is also in Phase-III testing.

Another new drug in development and testing is ACP-104 by Acadia Pharmaceuticals (Phase II)
Medical Benefit: ACP-104 aims to deal with hallucinations and delusions. Developers also hope the drug, taken in pill form, helps with difficulties in learning, memory and work performance. Acadia expects similar side effects as with other antipsychotic drugs, including obesity and cardiovascular problems.

Company Benefit: Acadia is also developing ACP-103, an adjunctive therapy for schizophrenia. Developers hope that medication reduces side effects of the antipsychotic drugs and improves their efficacy. Although not yet profitable, JMP Securities' biotech specialists predict ACP-104 and ACP-103 will make Acadia profitable by 2008.

Timing: The company anticipates results from its clinical programs for ACP-104 and ACP-103 in 2005

Sustained-release Seroquel/AstraZeneca PLC (Phase III)
Medical Benefit: Seroquel is an atypical antipsychotic, which helps control the abnormal thinking associated with schizophrenia. Already approved in tablet form and taken twice daily, trials are looking at Seroquel as a once-daily tablet in sustained-release formulation. This would simplify dosing and improve patient compliance, an AstraZeneca spokeswoman said. Trials show diminished side effects for already-approved Seroquel, particularly in weight gain, diabetes, restlessness and sexual problems. The company said it doesn't have results on any trials with the sustained-release form or information on its side effects.

Company Benefit: Seroquel tablet sales reached $1.5 billion in 2003 in the U.S., but the company declined to say how much they expect to make with the sustained-release form. Last year, AstraZeneca spent $3.45 billion on R&D.

Timing: The tablet form of Seroquel was approved to treat schizophrenia in 1997 and mania associated with bipolar disorder in 2003. A company spokeswoman declined to speculate when the sustained-release drug would be marketed

For a Full List of New Schizophrenia Drugs Click Here

For More information on Existing Schizophrenia Drugs Click Here

Posted by szadmin at March 24, 2005 06:26 PM

More Information on Schizophrenia Medications in Development


I would like to be sent any and all info on new helpful meds for schizophrenia.
Please help.
Thank you very much.

Posted by: John Sosa at May 30, 2005 12:00 PM

Please send me any information that you have on young adults with schizophrenia along with seizures. Thank you!!!

Posted by: Jami at July 8, 2005 03:35 PM

my son is 36 he has ocd bypolar,schizophinaand their is only one med left for him and it sends the white blood cells to his heart and could kill him]it is called lozapine their anything else,he is a dry acholic.plese if their is anyother medsthat can help he has hard voices for monthsand says he can't stand to live like this any more

Posted by: sylvia perkins at May 30, 2006 03:46 PM

i would like a list of all the older medications for schizophrenia and a list of the newer medications right after the older ones and a list of medications of the newest and the latetest and the ones that are still in progrss of becoming an approved medication for schizophrenia thank you very much and i want to know if its true what they say about clozapine that its the drug of choice for docters and to be used only as the last resort if nothing else works if that is true or not and i would like to know if you could tell me of a few or the more the better of medications for schizophrenia that are very effective with very few side effects if possible thank you

Posted by: junior at August 8, 2007 08:04 AM

Please send me a list of meds. I would like to know what my brother hasn't tryed yet. for every one els, god bless you and your loved one. I know what it's like.

Posted by: Ana Diaz at May 14, 2008 09:55 PM

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