April 15, 2005

Alcoholism & Schizophrenia

The Journal of the American Medical Association recently published a paper on this new drug that seems to allow people to quickly minimize their alcohol drinking. This is a new study on a drug that has yet to be FDA approved. This seems as though it could have potential value for those people suffering from dual diagnosis - people who have both schizophrenia and alcohol dependence.

Here is a short summary of the study (from the company press release/marketing department):

Once-monthly Injection of Vivitrex(R) Demonstrated Significant Reduction in Heavy Drinking in Conjunction with Counseling --

Alkermes, Inc. (Nasdaq: ALKS) today announced the publication of results from the Phase III clinical study of Vivitrex(R) (naltrexone long-acting injection), which showed that a once-monthly dose of Vivitrex in combination with counseling significantly reduced the median number of heavy drinking days in alcohol dependent patients from 19 days per month to three days per month. The study, led by nationally known investigators, is published in this week's issue of the Journal of the American Medical Association ("JAMA")(1) and represents one of the largest, most comprehensive clinical trials evaluating the use of medication for the treatment of alcohol dependence. The majority of the patients enrolled in the trial were actively and heavily drinking at study initiation.

Here is the full press releases: JAMA Publishes Positive Results of Alkermes' Phase III Study of Vivitrex in Alcohol Dependent Patients


I wanted to know if you knew of any facilities in the LA are that can treat patients dealing with both of these problems. My boyfriend and his family are currently trying to find a facility that can help his brother with the schizophrenia and his alcohol habits. Most places won't take him unless he stays on the daily medication for at least 3 months and you know that someone with such an illness is not totally capable of doing that. Especially if you struggle with hearing voices and they tell you its bad don't take it. Do you have any recommendations for us? Any place we can be referred to would be greatly appreciated.


Posted by: Griselda Zelaya at April 20, 2006 01:29 PM

I am a recovered alcoholic and my mother was schizophrenic. I remember once, when I was doing some research, reading that there was some evidence that linked, genetically, alcoholism and schizophrenia. Does anybody out there know about this?

Posted by: George A. Wolf at June 24, 2006 09:10 AM

Is this drug yet approved? if not can anyone participate in trials?

Posted by: sarah at January 9, 2008 09:13 PM

My father is an alchoholic and schizophrenic. Everytime he hears voices he takes a couple of xyprexa and 2-12 beers, instead of staying on his presribed daily dosage.

Posted by: Michelle at May 21, 2008 02:04 PM

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