October 12, 2005

The Causes of Schizophrenia

The August issue of Psychiatric Times has a very good summary of the current state of the scientific understanding of the causes of schizophrenia. If you are not fully up to date on this - we encourage you to read it:

The Role of Genetic and Environmental Factors in the Development of Schizophrenia
By Jonathan Picker, Ph.D.

"Schizophrenia appears to be a disorder of development that results from a series of neurological insults from fetal life onward (Rapoport et al., 2005). Whether or not schizophrenia manifests appears to be the result of a conglomeration of these factors, both genetic and environmental in origin (Sullivan et al., 2003).

No one factor appears to be most significant in the genesis of schizophrenia. This is evident despite the very significant resources that have been expended in the search to understand the patho-etiology of schizophrenia. This may be because there are multiple factors involved; multiple different disorders with varied pathologies present with the schizophrenia phenotype; or a combination of both. The search to uncover the pathological basis to schizophrenia has, however, provided broad generalizations that have yielded more specific etiological candidates as a result of newer, more powerful methodologies, particularly those resulting from the Human Genome Project. Interestingly, some of the genetic candidates identified providing explanatory models that may incorporate identified environmental risk factors."

To read the full story: The Role of Genetic and Environmental Factors in the Development of Schizophrenia

To read more about the individual risk factors see:

Environmental Factors linked to Schizophrenia


i think this report has been very instructed for my knowlodge...i wonder if it is possible for me to know
At what age it develope?if there is any child Schizophrenia?

Posted by: RAMON RUIZ at October 19, 2005 09:40 AM

Hi Ramon,

Schizophrenia typically hits males between the ages of 18 years and 25 years, and women about 10 years later.

There are cases of childhood schizophrenia - but they are quite rare (about one case for every 10,000 people (this compares to the typical frequency of schizophrenia of about 1 case per 100 people).

Posted by: Sz Administrator at October 19, 2005 11:28 AM


Im one of the victims of Schizophrenia.
I was hit by it for the first time at the age of 25.
Im 26 and married now.I would like to conceive in the next couple of months.Could you please let me know the appropriate age for me to conceive so that it might not get carried to my offspring.
PS: Im the first person in my family who have Schizophrenia.

Posted by: Leena at November 7, 2005 08:10 PM


my name is aaron. i am 13 and i'm trying to find out what mental disorder i have, cos im certain i have one.

i hear weird sounds sometimes and wake up to gunshots and big popping sounds that didnt happen... a little bit ago i woke up to the sound of being ran over by a car... sometimes i feel things touching me that arent really there, like hands touching my stomach when i have my shirt off... and sometimes i hear voices saying im gonna die and that they're gonna kill me... i have a hard time thinking usually... sometimes voices tell me to kill others... i always have dreams where im being chased by someone...

i really need help.. i've confronted my parents but they dont do anything about it...

Posted by: aaron at December 2, 2005 07:15 PM

i had schizophrenia three times before ,is there any thing i can do to prevent get the deases again?

Posted by: WAEL at December 10, 2005 04:06 AM

hi i was just wondering where your copyright information was.

Posted by: elizabeth at February 2, 2006 05:31 AM

i am doing a report on schizophrenia and i could use some more info if you have any e-mail it to me at trippchic69@yahoo.com thanx

Posted by: jordan at May 5, 2006 08:51 AM

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