November 02, 2005

Abilify Best for Treating Children?

Abilify (aripiprazole) was recently tested on 19 children from the ages of 10-17 who have schizophrenia or bipolar disorder. The children were given the same doses normally used for adults. At the end of the study, 17 of the patients were reported either "improved" or "much improved". More importantly, the drug did not appear to cause the metabolic side effects (weight gain, lipid dysregulation) usually associated with atypical antipsychotics. The most common side effects were blurred vision, excessive sleepiness or insomnia, and headache. These effects were usually temporary and did not appear to be dependent on the dose. The drug has not yet been approved by the FDA (Food and Drug Administration) for use in children. A larger study by the NIMH (National Institute of Mental Health), with comparisons with other medications would be much more valuable than a small study like this.

Source: Moyer, Paula. AACAP: Atypical Antipsychotic Scores at Adult Doses for Children and Adolescents. MedPage Today Oct 24, 2005

Related Articles:
Treatment of Adolescent and Child Schizophrenia
ACP-104 Future Schizophrenia Drug
Aripiprazole and EPS?
Atypical Antipsychotics Affect Blood Glucose Levels
Introduction and FAQ (child onset schizophrenia)



I started out on 5mg of Abilify, and now I am on 10mg. I have had good results, except for minor loose associations of thought. I have stopped drinking orange juice, because of grapefriut juice concerns about Abilify. I wonder if orange juice should be a concern amoung those taking Abilify. I also have tried the mineral supplement Selenium(100mcg), and Folic acid, this seem to affect the minor loose associations of thought, and it improved my self-confidence. It did not have a anti-psychotic effect.

Posted by: Ken1 at April 18, 2006 02:26 PM

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