Internet-based Audio and Video Files on Schizophrenia and Related Issues
Biology of Schizophrenia

Schizophrenia – What is Schizophrenia and Causes - Molecular and Genetic Factors
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File Type: Real Media. Download player here
File Source: NIMH, US Government

File Date
: Tuesday, March 30, 2004

Author/Sponsor: Michael Egan and Chris Austin
Bandwidth: 384 Kbps

The Science of Schizophrenia Play audio - click here
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File Source: National Public Radio

File Date
: July 31, 1998

Note: When you click on the audio link above, a new window will open up on your web browser. To listen to the Audio file, click on the link that says "Talk of the Nation audio."

In this hour, we'll take a look at the science of schizophrenia, the challenges of treating people with this disease, and how the legal system deals with the mentally ill. Studio guests include the Executive Director of NAMI in Arlington, VA, the Director of Psychiatric Research at UC Irvine medical school, and the Executive Director of the Mental Health Association of Southeastern Pennsylvania.

The Genetics of Schizophrenia Play audio - click here
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File Source: National Public Radio

File Date
: May 6, 1999

Note: When you click on the audio link above, a new window will open up on your web browser. To listen to the Audio file, click on the link that says "Morning Edition audio."

Study linking schizophrenia with a genetic component in DNA. It's not a new idea--scientists have been studying it for a decade at least--but now the focus is on families where schizophrenia occurs more frequently. The families are Ashkenazi Jews, and they are not united in their support for the study.

Schizophrenic Mice - Genetically Altered Rodents Teach Scientists About Disorder Play audio - click here
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File Source: National Public Radio
File Date
: March 3, 2003

Note: When you click on the audio link above, a new window will open up on your web browser. To listen to the Audio file, click on the link that says "Morning Edition audio."

More than two million people in the United States have schizophrenia, yet the disorder remains a medical mystery. Scientists don't know precisely what causes some brains to produce hallucinations, delusions and disordered thinking. One reason it's particularly hard to study schizophrenia is that it doesn't seem to occur in animals. But as NPR's Jon Hamilton reports, a small group of scientists at the National Institutes of Health are using genetic engineering to reproduce some of the symptoms of schizophrenia -- in mice. Note: When you click on the link below, a new window will open up on your web browser. To listen to the Audio file, click on the link that says "Morning Edition Radio."

The Neuroscience and Mental Illness Play Audio - click here
File Type: Real Media. Download player here
File Source: NIMH, US Government

File Length: 5 Hours, 22 minutes
File Date
: Wednesday, May 30, 2001

Speakers: R. Wyatt, D. Weinberger, S. Hyman, S. Snyder, P. Goldman-Rakic, B. Hoffer, F. Bloom, L. DeLisi, R. Desimone, W. Freed, J. Grebb, D. Luchins, J. Kleinman, K. Berman, S. Potkin, L. DeLisi
Bandwidth: 33 Kbps

Closed Worlds - Studying the Biology of Isolated Populations Play Audio - click here
File Type: Real Media. Download player here
File Source: BBC Radio
File Date
: April 15, 2003

In the last few years, Iceland has been put on the biotech map, with the founding of Decode Genetics, a company started by entrepreneurial businessman, Kari Steffanson. He believes that the unique genetic qualities of the Icelandic people, coupled with the meticulous medical and geneological records that the country has kept will lead to the discovery of genes associated with many common diseases such as stroke, diabetes, schizophrenia and heart disease.

Intervention trials of EFAs in Schizophrenia. Play Audio - click here
File Type: Real Media. Download player here
File Source: NIMH, US Government
File Date
: April 15, 2003

Author/Sponsor: Malcolm Peet, M.D., University of Sheffield, U.K.
Total Running Time: 21:27 minutes
Bandwidth: 33 Kbps

Psychiatric Genetics: A Current Perspective Play video - click here
File Type: Real Media. Download player here
File Source: UCLA grand rounds
File Date
: Nov 28, 2002
Speaker: Kenneth S. Kendler, MD, Director, Virginia Institute for Psychiatric and Behavioral Genetics

According to the genetic epidemiologist, a person's risk for psychiatric disorder is made up of three factors: genetic makeup, family environment, and individual environment. Dr. Kendler gives a review of two central paradigms in psychiatric genetics (genetic epidemiology and gene-finding methods), to address the central question of how genes raise a person's risk of developing a psychiatric problem.

The Revolution in Psychiatric Genomics: The Coming Era of New Treatments and Diagnoses
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File Type: Real Media. Download player here
File Source: UCLA grand rounds

File Date
: Oct 30, 2001
Speaker: John Kelsoe, MD, Associate Professor of Psychiatry, University of California, San Diego.

Although great strides have been made in the last 20 years thanks to the growing field of neuroscience, psychiatrists and patients alike would still like to see drugs with greater efficacy, fewer side effects, more rapid action, and a more predictable effect on patients. Dr. Kelsoe talks about how the genomics field will hopefully usher in some of these changes, introducing a new way of practicing psychiatry in the next 50 years.

Executive Function as a Core Feature of Schizophrenia Play video - click here
File Type: Quicktime video. Download player here.
File Source: University of Chicago grand rounds
File Date
: April 2001

Note: when you click on the video link above, a new browser window will open. Start the video by clicking on the picture of the presenter. If you can't see the picture, you need to download a quicktime video player.

Speaker Ivan J. Torres, PhD talks about the role of "executive function" (psychological processes necessary for goal-oriented behavior, control and regulation of behavior, and novel problem solving) in schizophrenia. Some research suggests that it could account for some of the disorder's broad, generalized deficits.

The Anatomy of Attention and Schizophrenia Play video - click here
File Type: Real Media. Download player here
File Source: UCLA grand rounds
File Date
: April 22, 2003
Speaker: Robert Bilder, Ph.D., Visiting Professor, Psychiatry and Biobehavioral Sciences; Chief, Medical Psychology-Neuropsychology, Neuropsychiatric Institute, David Geffen School of Medicine, University of California, Los Angeles.

Dr. Bilder introduces the "dual-trends" theory of the anatomy of attention, and highlights schizophrenia as an example of an attentional auto-regulation disorder. NOTE: this talk is very dense and technical from an anatomical and neurological standpoint. Appropriate for the viewer who has more than a passing interest (and experience) with neurobiology.

Psychopathology and Drug Discovery for Schizophrenia
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File Source: UCLA grand rounds

File Date
: Jan 27, 2004
Speaker: William T. Carpenter, Jr., MD, Professor of Psychiatry and Pharmacology, University of Maryland School of Medicine, Director, Maryland Psychiatric Research Center.

Dr. Carpenter takes a psychopathology approach to schizophrenia; he describes what psychopathologists feel schizophrenia is as a disorder, and the way that it should be treated.. He identifies three "domains" of the disease - psychosis, negative, and interpersonal - that he feels should be researched and treated as separate entities, even though they can clinically overlap.

Can Neuroimaging Be Used to Improve the Diagnosis of Schizophrenia?
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File Source: University of Chicago grand rounds
File Date
: Oct 20, 2003
Speakers: John G. Csernansky, MD; Gregory B. Couch, Professor of Psychiatry and Associate Professor of Neurobiology, Washington University.

Note: when you click on the video link above, a new browser window will open. Start the video by clicking on the picture of the presenter. If you can't see the picture, you need to download a quicktime video player.

The objectives of the presentation are: (1) to review recent current findings of neuroanatomical abnormalities in patients with schizophrenia, and; (2) to present new findings in brain structure abnormalities in schizophrenia patients, obtained using computer algorithms for anatomical analysis.

Progressive Brain Changes in Schizophrenia: Clinical Course and Interactions with Alcoholism
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File Type: Real Media. Download player here
File Source: Yale University grand rounds
File Date
: June 27, 2003
Speaker: Daniel H. Mathalon, Ph.D., MD, Assistant Professor of Psychiatry, Yale University School of Medicine.

Is schizophrenia a progressive degenerative disorder? Dr. Mathalon presents clinical and physical evidence (MRI and ERP studies) that support this hypothesis, showing changes to the brain over the course of the illness. He then discusses some factors that can help clinicians predict the progressive course of the disorder in certain patients.

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