March 27, 2006

Schizophrenia linked to Auto-immune Diseases

Read more... Schizophrenia Biology

The March issue of the American Journal of Psychiatry included a paper in which Dr. William W. Eaton, (Johns Hopkins University, Baltimore), and colleagues examined the association between schizophrenia and a range of autoimmune diseases by evaluating three databases.

Included in the analysis were 7704 people diagnosed with schizophrenia between 1981 and 1998 and their parents, as well as a ramdom sample of people chosen as controls and their parents.

It was reported that people with a history of one or more autoimmune diseases had a 45 percent higher risk of schizophrenia, according to the authors. Schizophrenia patients had a higher prevalence of nine autoimmune disorders compared with comparison subjects.

Compared with the parents of controls, the parents of schizophrenic patients had a higher prevalence of 12 autoimmune diseases, including -- thyrotoxicosis, celiac disease, acquired hemolytic anemia, interstitial cystitis, and Sjogren's syndrome.

"In future clinical studies, it may be interesting to search for a family history of autoimmune diseases ... in patients with schizophrenia," Eaton's team suggests. "Eventually, individual or family disease comorbidity may help to elucidate shared etiologic pathways."

Source: American Journal of Psychiatry


funny, in 36 years of being around this disease, i've never met a schizophrenic who had any of those diseases. there must be more to this than 'doing the math', LOL, and a '45 per cent risk' may not actually translate into daily life as 45 percent more occurances.

at various points in that 36 years, i have been told by researchers that schizophrenia increases the risk of a great many things, none of which turned out to hold h20.


Posted by: slc at April 10, 2006 04:24 PM

funny, in 12 years being with my schizophrenic son and nephew, i find this info amazing.....I have Sjogrens, grandmother and aunt both had autoimmune disease.
any study out there?..we are ready

Posted by: kb at June 15, 2007 12:25 PM

Post a comment

Please enter this code to enable your comment -
Remember Me?
(you may use HTML tags for style)
* indicates required