Schizophrenia Daily News Blog

Expert Interview with Dr. Seeman, Discoverer of Dopamine D2 Receptors

Thanks to Tim for directing us to this expert interview by Jessica Gould on Medscape, "Probing the Biology of Psychosis, Schizophrenia, and Antipsychotics: An Expert Interview With Dr. Philip Seeman, MD, PhD". (free registration required)

Dr. Seeman had spent 12 years searching for what in the brain antipsychotics were targeting, before he discovered the dopamine D2 receptors. In this interview, Ms. Gould questions Dr. Seeman about the significance of that and other key discoveries over the last 43 years.

Also discussed was the mechanism behind atypical antispychotics' lack of Parkinsonian side-effects as compared with the atypical antipsychotics, genetic biomarkers for "dopamine supersensitivity", and the involvement of NMDA receptors.

Read the Interview: Probing the Biology of Psychosis, Schizophrenia, and Antipsychotics: An Expert Interview With Dr. Philip Seeman, MD, PhD

Read More About Dr. Seeman's Research and Discoveries:
Psychotic Behavior Explained?
Gene Mutations and Schizophrenia