Schizophrenia Researchers - Following is a list of some of the researchers who are helping most to advance the science as well as the public understanding of schizophrenia. It's an exciting time in schizophrenia biology and genetics today - with advancements and research papers on many new genes involved in schizophrenia coming out on a monthly basis. The work being done by "Decode Genetics, Inc." in particular seems to be some of the most forward looking and progressive. Decode's work represents the first time a gene has been identified by two independent studies to be associated with schizophrenia.
Dr. E. Fuller Torrey - Stanley Medical Research Institute
Early Psychosis Treatment Guide - Year 2002, University of British Columbia - Note: this is a large (3 MB) PDF file and it may take a few minutes to download if you have a slow internet connection).
Recommended Advanced Books on the Biology of Schizophrenia
These books cover the science, biology and genetics of schizophrenia. "Nature via Nurture", while not specifically a book about schizophrenia - has an entire chapter (Chapter 4 - The Madness of Causes) on the genetics and environmental influences of schizophrenia. Overall, the book is a well-written and very enjoyable book about the interplay of genes and environment in human development. Dr. Nancy Andreason's and Dr. Irv Gottesman's books are good in-depth college-level books covering schizophrenia by two of the leading researchers that are focused on schizophrenia.
Psychiatric Genetics and Genomics by Peter McGuffin (Editor), Michael J Owen (Editor), Irving I Gottesman (Editor), Publisher: Oxford University Press; (December 2, 2002), ISBN: 0192631489
Brave New Brain: Conquering Mental Illness in the Era of the Genome by Nancy C. Andreasen, Publisher: Oxford University Press; (April 2001) ISBN: 0195145097 (HARDCOVER) "Excellent introductions to neuroscience, brain imaging, and genetics. Outstanding overviews of what is known about the neuroscience and genetics of the major psychiatric disorders of schizophrenia, mood disorders, dementia, and anxiety disorders. The descriptions of the history and neuroscience of medication are especially good."--Nature
The BROKEN BRAIN by Nancy C. Andreasen (Author), Publisher: Perennial; Reprint edition (November 1985) ISBN: 0060912723 (Note: this is an old book -- over 15 years old -- and should only be referenced if the more recent books listed above are not available. Information in the field of genetics is progressing rapidly, and a book that is 15 years old is truly ancient).
Recommended Professional Books on Schizophrenia and Psychiatric Drugs
Psychiatric Genetics and Genomics by Peter McGuffin (Editor), Michael J Owen (Editor), Irving I Gottesman (Editor), Publisher: Oxford University Press; (December 2, 2002), ISBN: 0192631489
Practice Guidelines for the Treatment of Patients with Schizophrenia by American Psychiatric Association, APA, Publisher: Amer Psychiatric Pr; 1st edition (January 15, 1997) ISBN: 0890423091. Developed by experts on schizophrenia and exhaustively reviewed by APA members, the American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia provides therapists with a set of patient care strategies that will aid their clinical decision making. Note: This publication is usually available on-line for free at: The American Psychiatric Association website
Schizophrenia by Steven R. Hirsch (Editor), Daniel R. Weinberger (Editor), Penny R. Mitchell, Publisher: Blackwell Publishers; 2nd Revision edition (March 2003) ISBN: 0632063882
Insight and Psychosis by Xavier F. Amador (Editor), Anthony S. David (Editor), David Amador, Publisher: Oxford University Press; (January 1998) ISBN: 0195084977
Paranoid schizophrenia - These persons are very suspicious of others and often have grand schemes of persecution at the root of their behavior. Halluciations and delusions are prominent.
Disorganized schizophrenia (Hebephrenic Schizophrenia) - In this case the person is verbally incoherent and may have moods and emotions that are not appropriate to the situation. Hallucinations are not usually present.
Catatonic schizophrenia - In this case, the person is extremely withdrawn, negative and isolated, and has marked psychomotor disturbances.
Residual schizophrenia - In this case the person is not currently suffering from delusions, hallucinations, or disorganized speech and behavior, but lacks motivation and interest in day-to-day living.
Schizoaffective disorder - These people have symptoms of schizophrenia as well as mood disorder such as major depression, bipolar mania, or mixed mania.
Undifferentiated Schizophrenia - Conditions meeting the general diagnostic criteria for schizophrenia but not conforming to any of the above subtypes, or exhibiting the features of more than one of them without a clear predominance of a particular set of diagnostic characteristics.
Schizophrenia Genetics, Research Organizations, and Related Information
Schizophrenia Genetics
Database for Schizophrenia candidate genes - "The Database for Schizophrenia candidate genes focusing on Variations(VSD) includes the genes that contains polymorphisms related with schizophrenia. Has also information about the metabolic pathways in an easy-to-use interface."
Decode Genetics, Inc.(Iceland) Note: The founder of Decode Genetics, Dr. Stefansson has a considerable emotional investment in the disease because his elder brother has schizophrenia.